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Methotrexate was developed in the early 1950’s and scientists have spent the last 6 decades bringing the efficacy and safety of this medication up to standard. Methotrexate works by impeding the growth of certain cells in the body - in particular cells which reproduce quickly, such as those of the skin and bone marrow, and cancer cells. Because of this quality of Methotrexate, it is very effective for the treatment of various types of cancer, including breast, skin or lung cancer and leukemia. In addition, studies have proven Methotrexate can be effectively used against severe cases of psoriasis and rheumatoid arthritis. In all these cases, Methotrexate is especially useful for patients who have tried other medications without much success.


Due to the nature of this medication, we strongly recommend delivery by courier service, which can be tracked online and only takes 4-7 business days.



Manufacturer: Cipla
Brand Name: Rheumatrex, Trexall, Imutrex

Average Delivery Time: 8 days
Exp.Date: -
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   Methotrexate 2.5 Mg
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  • Effective for the treatment of various types of cancer, including skin cancer, lung cancer and leukemia
  • Can also be used for the treatment of severe cases of psoriasis and rheumatoid arthritis
  • Works for patients who have tried other medication without success
  • Also useful for the treatment of diseases caused by an overactive immune system, such as Crohn’s Disease and Multiple Sclerosis
  • Can succesfully treat ectopic pregnancies


Product information

Product Description
Safety Information
Side Effects


How does Methotrexate work?

Methotrexate is very effective in inhibiting the enzyme dihydrofolate reductase (DHFR), which plays an important role in the DNA and RNA synthesis. It therefore impedes the growth of certain cells in the body, especially those which rapidly reproduce, such as malignant cells responsible for cancer.


What should I discuss with my healthcare professional before taking Methotrexate?

Notify your doctor if you suffer from any of the following:

  • A kidney disease
  • A liver disease
  • A lung disease
  • Pneumonia
  • Stomach ulcers
  • Any kind of infection
  • A blood cell disorder like anemia or leucopenia

If you are receiving radiation treatments you may need to have extra tests and your doctor will adjust your dosage in accordance with your health and risk level.


Is it safe to take Methotrexate while pregnant or breastfeeding?

Methotrexate is classed as Pregnancy Category X by the FDA, which means that use by both men and women can cause birth defects in an unborn child. Women should take a pregnancy test before starting to use Methotrexate and inform their doctor immediately if they become pregnant and either they or their partner is currently taking Methotrexate. Both men and women should use birth control to prevent pregnancy while taking Methotrexate. You should use this birth control for at least 90 days or one ovulation cycle after treatment is over before removing these precautions.
Methotrexate also passes into breast milk and should not be used while nursing an infant.  If you are currently breastfeeding your baby, you should speak with your doctor before taking Methotrexate. You may need to discontinue breastfeeding if it is deemed necessary for you to take Methotrexate as it could harm your baby if ingested.


What should I avoid when taking Methotrexate?

Avoid sunlight exposure or artificial UV rays (tanning and sunlamps beds) while taking Methorexate, and especially while being treated for psoriasis. Methotrexate can make your skin much more sensitive to sunlight, and it could worsen your condition.


Can I drink alcohol while using Methotrexate?

You should not drink alcohol while using Methotrexate. The combination of alcohol and Methotrexate can be dangerous and could cause liver damage or cirrhosis, especially when alcohol is consumed regularly. However, even small amounts of alcohol should be avoided while taking Methotrexate, as there is no known basis to determine what a ‘safe’ level of alcohol would be or even if there is a ‘safe’ level.


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